The Mindy Project places a clear emphasis on its lead character's identity as a woman of color in the male-dominated world of medicine. While the show largely maintains character-driven narratives, it does sometimes foreground diversity topics and representation over organic story development, though rarely at the expense of humor or plot coherence.

The series often pokes fun at traditional gender roles, portraying masculinity as buffoonish and highlighting modern, urban female independence. Family and religion exist more as background flavor than meaningful sources of conflict or morality, making tradition feel sidelined and sometimes gently mocked.

Dissenting or more traditional viewpoints are present but usually played for laughs or caricatured. The show's moral universe is squarely urban and progressive, but it's not aggressively hostile toward alternative perspectives, more dismissive than villainizing.